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Coagulation factor XI protease domain in complex with active site inhibitor

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Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6ts4
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Coagulation factor XI protease domain in complex with active site inhibitor Descriptor: 2-[2-[[3-[3-(aminomethyl)phenyl]phenyl]carbonylamino]phenyl]ethanoic acid, Coagulation factor XI, DIMETHYL SULFOXIDE, ... Authors: Renatus, M, Schiering, N. Deposit date: 2019-12-19 Release date: 2020-07-08 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.17 Å) Cite: Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach. J.Med.Chem., 63, 2020
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2019-12-19
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