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Structure of human Programmed cell death 1 ligand 1 (PD-L1) with low molecular mass inhibitor

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Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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Structure of human Programmed cell death 1 ligand 1 (PD-L1) with low molecular mass inhibitor Descriptor: (2~{R})-2-[[2-[(3-cyanophenyl)methoxy]-4-[[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methyl-phenyl]methoxy]-5-methyl-phenyl]methylamino]-3-oxidanyl-propanoic acid, 1,2-ETHANEDIOL, Programmed cell death 1 ligand 1 Authors: Zak, K.M, Grudnik, P, Skalniak, L, Dubin, G, Holak, T.A. Deposit date: 2017-03-27 Release date: 2017-12-06 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the PD-L1-induced exhaustion of T-cells. Oncotarget, 8, 2017

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2017-03-27
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