"该数据集主要为了寻找参与调控AR和GR稳定性的关键成员。利用外界刺激处理前列腺癌细胞系，使得 AR 和 GR 处于不同的稳态，进而通过免疫共沉淀-质谱鉴定的方式，比较不同外界刺激下 AR 或 GR 结合的蛋白质机 器差异，获得通过相互作用直接调控 AR 或 GR 稳态的蛋白质机器组分。数据量11 MB"
Recruitment of PLC-gamma by FGF receptors has been best studied in FGFR1c signaling, where it has been shown that autophosphorylation of Tyr766 in the C-terminal tail of FGFR1c creates a specific bind
The regulatory subunit (p85) of PI3K interacts directly with phosphorylated Y721 of KIT via one of its SH2 domains. This binding leads to the activation of the catalytic domain (p110) of PI3K. SCF-ind
