Peak expression and time point of candidate genes associated with IFN response that were modulated in IFNα2 pre-treated macrophages compared to untreated control and modulated by HIV-1.

Selection of the top 500 most modulated genes when comparing the IFNα2 pre-treated macrophages infected or not with HIV-1. Of these, 55 were related to interferon as a keyword. From these 55, 21 were upregulated by interferon as compared to untreated control (peak expression and time point) but modulated differentially when HIV-1 was added. Those genes may represent interferon effectors that are modulated by HIV-1 infection during the interferon response.