Src family kinase Hck with bound inhibitor A-420983

Protein Data Bank Japan2024-10-16 更新2026-03-21 收录

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https://pdbj.org/mine/summary/2c0i

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Src family kinase Hck with bound inhibitor A-420983 Descriptor: CALCIUM ION, N-(4-{4-AMINO-1-[4-(4-METHYLPIPERAZIN-1-YL)-TRANS-CYCLOHEXYL]-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL}-2-METHOXYPHENYL)-1-METHYL-1H-INDOLE-2-CARBOXAMIDE, TYROSINE-PROTEIN KINASE HCK Authors: Borhani, D.W, Burchat, A, Calderwood, D.J, Hirst, G.C, Li, B, Loew, A. Deposit date: 2005-09-03 Release date: 2006-09-20 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Discovery of A-770041, a Src-Family Selective Orally Active Lck Inhibitor that Prevents Organ Allograft Rejection. Bioorg.Med.Chem.Lett., 16, 2006

创建时间：

2005-09-03