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Ligand-Controlled Ni(0)–Al(III) Bimetal-Catalyzed C3–H Alkenylation of 2‑Pyridones by Reversing Conventional Selectivity

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NIAID Data Ecosystem2026-03-12 收录
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Conventional C–H alkenylation with alkynes via low-valent transition-metal catalysis occurs at the C6 or C4 position of 2-pyridone with electron-deficient C–H bonds. A bifunctional ligand-bonded Ni–Al bimetallic catalyst resulted in a reversed selectivity, providing a series of C3-alkenylated 2-pyridones in up to 99% yields.

创建时间:
2021-04-01
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