Crystal structure of beta-secretase 1 in complex with selective beta-secretase 1 inhibitor
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Crystal structure of beta-secretase 1 in complex with selective beta-secretase 1 inhibitor Descriptor: Beta-secretase 1, N-[4-(1-BENZYLCARBAMOYL-2-METHYL-PROPYLCARBAMOYL)-1-(3,5-DIFLUORO-PHENOXYMETHYL)-2-HYDROXY-4-METHOXY-BUTYL]-5-(METHANES ULFONYL-METHYL-AMINO)-N'-(1-PHENYLETHYL)-ISOPHTHALAMIDE, SULFATE ION Authors: Borkakoti, N, Lindberg, J, Nystrom, S. Deposit date: 2009-09-04 Release date: 2010-03-02 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Design and Synthesis of Potent and Selective BACE-1 Inhibitors. J.Med.Chem., 53, 2010
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2009-09-04
