Stereoselective Synthesis of Fused Aziridines via One-Pot Sequential Decarboxylative Mannich Reaction and Oxidative C–H Amination of Cyclic Imines with β‑Ketoacids
收藏NIAID Data Ecosystem2026-03-09 收录
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A novel one-pot sequential transformation via decarboxylative Mannich reaction (DMR) and oxidative C–H amination of cyclic imines with β-ketoacids is described. This methodology has been utilized to provide access to fused aziridines with excellent diastereoselectivity. Several examples of catalytic enantioselective sequential transformation are presented.
创建时间：
2016-02-04
