Crystal structure of KIT kinase domain with a small molecule inhibitor, PLX3397
收藏Protein Data Bank Japan2023-10-18 更新2026-03-21 收录
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Crystal structure of KIT kinase domain with a small molecule inhibitor, PLX3397 Descriptor: 5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-{[6-(trifluoromethyl)pyridin-3-yl]methyl}pyridin-2-amine, Mast/stem cell growth factor receptor Kit Authors: Zhang, Y. Deposit date: 2020-10-21 Release date: 2021-07-07 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Association of Combination of Conformation-Specific KIT Inhibitors With Clinical Benefit in Patients With Refractory Gastrointestinal Stromal Tumors: A Phase 1b/2a Nonrandomized Clinical Trial. Jama Oncol, 7, 2021
创建时间：
2020-10-21
