Mishra et al., Rehydration rescues Il22-/- mice from lethal Citrobacter rodentium infection, 2025
收藏Figshare2025-10-21 更新2026-04-28 收录
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https://figshare.com/articles/dataset/Mishra_et_al_Rehydration_rescues_i_Il22_i_sup_em_-_-_em_sup_mice_from_lethal_i_Citrobacter_rodentium_i_infection_2025/29980600
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资源简介:
IL-22 is considered essential for host survival during C. rodentium infection, yet the cause of death was not well understood. Here, we show that Il22-/- mice succumb due to dehydration, and that Fluid therapy prevents mortality, revealing IL-22-independent recovery mechanisms. These findings overturn the prevailing paradigm that IL-22 is indispensable for host survival, redefining its role in mucosal immunity.
创建时间:
2025-10-21



