首页/数据集/TIA-proteins suppress cell and tumor growth via promoting select p53 gene targets-mediated cell cycle arrest and apoptosis

TIA-proteins suppress cell and tumor growth via promoting select p53 gene targets-mediated cell cycle arrest and apoptosis

ChEBI2015-03-05 更新2026-07-21 收录

p53信号通路

肿瘤抑制机制

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-51500 数据链接链接失效反馈

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TIA-proteins suppress cell and tumor growth via promoting select p53 gene targets-mediated cell cycle arrest and apoptosis

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2015-03-05

细胞凋亡机制

p53信号通路

17β-Estradiol (E2) is the major estrogen secreted by the premenopausal ovary and shows dual effects on cell apoptosis under pathological conditions. E2 was previously shown to increase CD38 mRNA and p

NIAID Data Ecosystem260

Common Tumor Suppressive Signaling of Thyroid Hormone Receptor Beta in Breast and Thyroid Cancer Cells

肿瘤抑制机制

转录组学分析

The thyroid hormone receptor beta (TRÃ) is a tumor suppressor in multiple types of solid tumors, most prominently in breast and thyroid cancer. An increased understanding of the molecular mechanisms

NIAID Data Ecosystem90

PLTP is a p53 target gene with roles in cancer growth suppression and ferroptosis

肿瘤抑制机制

铁死亡调控

The tumor suppressor protein p53 suppresses cancer by regulating processes such as apoptosis, cell cycle arrest, senescence, and ferroptosis. Whereas numerous p53 target genes have been identified, o

NIAID Data Ecosystem50

Histone chaperone HIRA orchestrates H4K16ac-decorated dynamic chromatin in senescent cells and is required for suppression of oncogene-induced neoplasia.

细胞染色质动态

肿瘤抑制机制

Cellular senescence is a stable proliferation arrest that suppresses tumorigenesis. Histone chaperone HIRA deposits nucleosome-destabilizing histone variant H3.3 into chromatin in a DNA replication-in

NIAID Data Ecosystem90

SOLUTION NMR STRUCTURE OF TUMOR SUPPRESSOR P16INK4A, RESTRAINED MINIMIZED MEAN STRUCTURE

蛋白质结构解析

肿瘤抑制机制

SOLUTION NMR STRUCTURE OF TUMOR SUPPRESSOR P16INK4A, RESTRAINED MINIMIZED MEAN STRUCTURE Descriptor: TUMOR SUPPRESSOR P16INK4A Authors: Byeon, I.-J.L, Li, J, Ericson, K, Selby, T.L, Tevelev, A, Kim, H

Protein Data Bank Japan2024-05-22 更新50

TIA-proteins suppress cell and tumor growth via promoting select p53 gene targets-mediated cell cycle arrest and apoptosis

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