Poly (ADP-ribose) polymerase 1 (PARP-1) is a critical enzyme involved in DNA damage repair and recombination, and shows great potential for drug development in the treatment of cancers with defective
Early and late apoptosis measured by annexin V and propidium iodide staining in human breast cancer cells revealed that the metastatic MDA-MB-231 cells pretreated for 24 h with artesunate, became resi
We have screened our compound collection in an established cell based assay that measures the derepression of an epigenetically silenced transgene, the locus derepression assay. The screen led to the
Programs within NCI's Division of Cancer Treatment and Diagnosis (DCTD) provide a wide range of data for use to the scientific community. Bulk Data for Download
