Baseline characteristics of participants in the baseline only and longitudinal analysis cohorts.

†Baseline only = participants with only 1 DEXA performed; includes 14 screen failures.
‡TDF/placebo = participants randomized to TDF or placebo who had at least 1 follow-up DEXA and were included in the longitudinal cohort.
*P value compares TDF vs. placebo arms of longitudinal cohort.
¥For baseline only group, alcohol and recreational drug use data available for 12/26 participants who enrolled in the study.

DEXA, dual energy X-ray absorptiometry; TDF, tenofovir disoproxil fumarate; BMD, bone mineral density.