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Malformins produced by fungi from seagrass. Aspergillus tubingensis strain:IFM 63452

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NIAID Data Ecosystem2026-03-09 收录
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Malformin A1, a known cyclic pentapeptide, was isolated from the seagrass-derived fungus Aspergillus tubingensis. The identity of the compound was established based on LC-MS and 1H NMR data. Biological profiling revealed that malformin A1 exhibits trypanocidal activity against Trypanosoma congolense (IC50: 15.08 ng/mL) and cytotoxicity against HeLa (IC50: 50.15 ng/mL) and P388 (IC50: 70.38 ng/mL) cell lines.

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2016-07-13
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