Crystal structure of SARS-CoV-2 (Covid-19) Nsp3 macrodomain in complex with NDPr

Crystal structure of SARS-CoV-2 (Covid-19) Nsp3 macrodomain in complex with NDPr Descriptor: Non-structural protein 3, {(2R,3S,4R,5R)-5-[(8S)-4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl]-5-cyano-3,4-dihydroxyoxolan-2-yl}methyl [(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl dihydrogen diphosphate Authors: Wallace, S.D, Bagde, S.R, Fromme, J.C. Deposit date: 2024-03-11 Release date: 2024-05-01 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (1.395 Å) Cite: GS-441524-Diphosphate-Ribose Derivatives as Nanomolar Binders and Fluorescence Polarization Tracers for SARS-CoV-2 and Other Viral Macrodomains. Acs Chem.Biol., 19, 2024