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ACP2 crosslinked to the KS of the loading/condensing region of the CTB1 PKS

NIAID Data Ecosystem2026-05-02 收录

聚酮类生物合成

蛋白质交联

数据链接：

https://www.rcsb.org/structure/6FIK 数据链接链接失效反馈

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资源简介：

ACP2 crosslinked to the KS of the loading/condensing region of the CTB1 PKS

应用场景：

创建时间：

2025-07-09

蛋白质交联

药物抑制

Signal for non-crosslinked and crosslinked proteins was measured (See Fig 8). Inhibition was measured by determining the ratio of crosslinked to non-crosslinked signal. Data were normalized to the con

NIAID Data Ecosystem90

FkbI for Biosynthesis of Methoxymalonyl Extender Unit of Fk520 Polyketide Immunosuppresant

聚酮类生物合成

抑制剂开发

FkbI for Biosynthesis of Methoxymalonyl Extender Unit of Fk520 Polyketide Immunosuppresant

NIAID Data Ecosystem50

Exhaustively Identifying Cross-Linked Peptides with a Linear Computational Complexity

蛋白质交联

质谱数据分析

Chemical cross-linking coupled to mass spectrometry is a powerful tool to study protein–protein interactions and protein conformations. Two linked peptides are ionized and fragmented to produce a tand

NIAID Data Ecosystem40

Exhaustively Identifying Cross-Linked Peptides with a Linear Computational Complexity

质谱分析

蛋白质交联

NIAID Data Ecosystem70

Synthetic Studies toward A-74528

聚酮类生物合成

有机合成方法

A potentially biomimetic approach toward the complex polyketide A-74528 is described. It is based on highly substituted biaryl compounds, synthesized using advanced cross-coupling and condensation met

NIAID Data Ecosystem50

ACP2 crosslinked to the KS of the loading/condensing region of the CTB1 PKS

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