We report a previously unrecognized role of SAPCD2 in E2F signaling pathway in neuroblastoma. To explore SAPCD2-dependent gene regulation, RNA-seq analysis was conducted and the differently expressed
Gene expression is regulated by promoters and enhancers marked by histone H3-lysine-27 acetylation (H3K27ac), which is established by the paralogous histone acetyltransferases (HATs), EP300 and CBP. T
To understand the cross-lineage transition of neuroblastoma. We performed RNA sequencing for bulk tissue of tumor xenografts Overall design: RNA sequencing for bulk tissue of neuroblastoma cell xenogr
Analysis of the effect of shRNA-mediated knockdown of TRPM7 on gene expression levels in SH-SY5Y and SH-EP2 human neuroblastoma cells. Results were used for the identification of neural-crest-associat
MYCN’s expression levels without some or all of the listed mutations of MYCN and ALK were derived from an experimental study [90].vThe wild-type MAPK/RAS pathway’s signalling activity was derived from