Molecular Signatures Underlying Selective Regional Vulnerability to Alzheimer's Disease
收藏官方服务：
资源简介：
Molecular Signatures Underlying Selective Regional Vulnerability to Alzheimer's Disease
应用场景：
创建时间：
2016-08-19
相关数据集
Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and -independent cellular responses in Alzheimer's disease [7 months]
Glia have been implicated in Alzheimer's disease (AD) pathogenesis. Variants of the microglia receptor TREM2 increase AD risk and activation of âdisease-associated microgliaâ (DAM) is dependent on
NIAID Data Ecosystem50
Table_1_Benign Regulation of the Astrocytic Phospholipase A2-Arachidonic Acid Pathway: The Underlying Mechanism of the Beneficial Effects of Manual Acupuncture on CBF.DOC
BackgroundThe astrocytic phospholipase A2 (PLA2)-arachidonic acid (AA) pathway is crucial in understanding the reduction of cerebral blood flow (CBF) prior to cognitive deterioration. In complementary
NIAID Data Ecosystem10
Data Sheet 1_Western diet-induced visceral adipose tissue inflammation promotes Alzheimer’s disease pathology via microglial activation in a mouse model.docx
IntroductionWestern diet (WD)-induced visceral adipose tissue (VAT) inflammation is characterized by adipocyte hypertrophy, hypoxia, and apoptosis. Epididymal white adipose tissue (eWAT), a representa
NIAID Data Ecosystem00
The cryo-EM structure of AV-45 bound type3 amyloid beta 42 fibril.
The cryo-EM structure of AV-45 bound type3 amyloid beta 42 fibril. Descriptor: P3(40) Authors: Zhao, Q.Y, Tao, Y.Q, Liu, C, Li, D. Deposit date: 2023-08-15 Release date: 2024-08-21 Last modified: 2025
Protein Data Bank Japan2025-07-02 更新20
Exercise alleviates cognitive dysfunction in Alzheimer's disease mice via skeletal muscle-derived extracellular vesicles which enhance plaque clearance by microglia [RNA-Seq]
Exercise confers cognitive benefits in Alzheimer's disease (AD), yet the underlying mechanisms remain incompletely understood. The skeletal muscle functions as an endocrine organ that secretes myokine
NIAID Data Ecosystem00
