Global methylation in Arabidopsis plants after multigenerational exposure to high temperatures

We conducted whole-genome bisulfite sequencing (WGBS) of Arabidopsis thaliana mutation accumulation (MA) lines under different temperature treatments over sucessive generations, and then we identified the global methylation in each MA line. Our result showed taht DNA methylation was observed more frequently at DNA mutation sites, indicating its contribution to the mutation process at elevated temperatures. Whole-genome bisulfite sequencing (WGBS) of Arabidopsis MA lines at different temperature treatments over sucessive generations.