Collection of bibliography included in the study; Co-occurrence matrix set of subject words included in the study; Opportunity code; Trust code; Triple, Code of open triangle and closed triangle; Code run and software calculation result set

This study selected the relevant literature related to the adverse drug reactions of metformin from 1991 to 2020 as the data source, divided the time segment with a period of 3 years, and obtained the title information (see the title collection of the literature included in the study. zip), and then extracted the subject words through the bicomb2021 software to construct the co-occurrence matrix, and a total of 10 co-occurrence matrices were obtained (see the subject word co-occurrence matrix collection included in the study. zip). Import the 10 co-occurrence matrices into the self-designed python code and r code (see opportunity code. zip; trust code. zip; open triangle and closed triangle code. zip) to obtain the opportunity, trust value and the number of edge triangles of each node pair in the 10 networks. Use GePhi0.9.7 software to calculate the motivation value of the node pair, use Excel to calculate the global clustering coefficient of each network, and the edge clustering coefficient of each node pair, The number of edge triangles of each node pair is built by using excel software to construct the scatter diagram of node pair opportunity, trust, motivation value and node pair edge clustering coefficient, and the correlation between node pair opportunity value and edge clustering coefficient is calculated by using spss software, as well as the correlation between node pair trust, motivation value and edge clustering coefficient, and the number of closed triangles of node pair (see code operation and software calculation result set. zip).Select the literature bibliography data from 2000 to 2009 to build the panel data (see the literature bibliography collection included in the study. zip), and also use the self-designed python code and r code (see opportunity code. zip; trust code. zip; open triangle and closed triangle code. zip) to get the opportunity, trust value and the number of edge triangles of each node pair in 10 networks, and use GePhi0.9.7 software to calculate the motivation value of node pairs Proximity centrality, intermediary centrality, feature vector centrality and average path length of node pairs are imported into Stata/MP 17.0 software to obtain the correlation between node attributes and network characteristics (see code operation and software calculation result set. zip).The data contained in each data name is described in detail:1. Collection of bibliographies included in the studyThe data collection contains two folders, named the literature collection from 1991 to 2020 and the literature collection from 2000 to 2009. The literature collection from 1991 to 2020 stores the bibliographic data of 10 time periods from 1991 to 2020, and the literature collection from 2000 to 2009 stores the bibliographic data of 10 overlapping windows from 2000 to 2009.2. Co-occurrence matrix set of subject words included in the studyThe data set contains two folders, named the 1991-2020 subject word co-occurrence matrix set and the 2000-2009 subject word co-occurrence matrix set. The subject word co-occurrence matrix of 1991-2020 contains the subject word co-occurrence matrix of 10 time segments from 1991-2020. The first row and first column of each co-occurrence matrix are subject words, and the number represents the number of co-occurrence times of the subject word pair. The subject word co-occurrence matrix set in 2000-2009 stores the subject word co-occurrence matrix of 10 time windows in 2000-2009.3. Opportunity Code.zipThis code is used to calculate the opportunity value of node pair. The input data is co-occurrence matrix, and the input format is. csv format.4. Trust Code.zipThis code is used to calculate the opportunity value of node pair. The input data is co-occurrence matrix, and the input format is. csv format.5. Code of open triangle and closed triangle.zipThis code is used to calculate the number of closed triangles and open triangles on the side of the node pair. The input data is the co-occurrence matrix, and the input format is. csv format.6. Code run and software calculation result set.zipThe data set contains two folders, named 1991-2020 calculation results and 2000-2009 calculation results. The 1991-2020 calculation results store the calculation results and scatter diagrams of 10 time segments in 1991-2020. Take 1991-1993 as an example, the first row of each table is marked with the opportunity, comprehensive trust, motivation, edge clustering coefficient, and the number of closed triangles. At the end of each table, the mean value of opportunity, trust, motivation and Pearson correlation coefficient with edge clustering coefficient and the number of closed triangles are calculated.The 2000-2009 folder stores the panel data and the opportunity, trust, motivation of the stata software calculation, and the correlation between the node attributes and the network characteristics of the node.