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Practical Preparation and Resolution of 1-(2‘-Diphenylphosphino-1‘-naphthyl)isoquinoline: A Useful Ligand for Catalytic Asymmetric Synthesis

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NIAID Data Ecosystem2026-03-06 收录
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https://figshare.com/articles/dataset/Practical_Preparation_and_Resolution_of_1-_2_-Diphenylphosphino-1_-naphthyl_isoquinoline_A_Useful_Ligand_for_Catalytic_Asymmetric_Synthesis/3577983
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资源简介:
A practical synthesis of the atropisomerically chiral ligand QUINAP is described, followed by its efficient resolution into enantiomers by employing a deficiency of the chloropalladium complex derived from 1‘-(R)-1‘-(dimethylamino)-1-ethylnaphthalene. The X-ray structure of the ligand, which crystallises as a conglomerate, is reported.
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2016-08-12
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