β-Elemene derivatives produced from SeO2-mediated oxidation reaction
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http://datadryad.org/dataset/doi%253A10.5061%252Fdryad.cnp5hqc1w
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资源简介：
We report herein the first access of ß-elemene derivatives through the SeO2-mediated oxidation reaction. Several new compounds were isolated through such one-step reaction, and their structures were elucidated using various 2D-NMR techniques. This method provides easy access to multiple oxidative ß-elemene derivatives in one single step, and represents the first cyclohexyl ring modifications of ß-elemene. It’s expected to open up the opportunity for future derivatization on cyclohexyl ring of ß-elemene. The new compounds obtained above showed better anti-proliferation activities on several cancer cell lines than ß-elemene itself.
Methods
The 1H NMR, 13C NMR, 1H-1H COSY, 1H-1H NOESY, HMBC, HSQC are recorded in 500 MHz NMR machine. The data were processed in MestReNova software.
创建时间：
2020-04-03
