Ideal Thiolate-Zinc Coordination Geometry in Depsipeptide Binding to Histone Deacetylase 8
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Ideal Thiolate-Zinc Coordination Geometry in Depsipeptide Binding to Histone Deacetylase 8 Descriptor: Histone deacetylase 8, Largazole, POTASSIUM ION, ... Authors: Cole, K.E, Dowling, D.P, Christianson, D.W. Deposit date: 2011-04-28 Release date: 2011-08-24 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.143 Å) Cite: Structural basis of the antiproliferative activity of largazole, a depsipeptide inhibitor of the histone deacetylases. J.Am.Chem.Soc., 133, 2011
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2011-04-28
