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Transcriptomic analysis of primary human hepatic stellate cells undergoing TGFb mediated activation and JQ1 mediated attenuation of activation

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE117329
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资源简介:
Comparison of longitudinal transcriptomic profiles of activated human primary hepatic stellate cells to activated human primary hepatic stellate cells that are treated with anti-fibrotic inhibitor reveals inflammatory signaling as a key pathway that is modulated during pro-fibrotic activation and repressed during attenuation of fibrotic response. Longitudinal examination of TGFb treated or TGFb and JQ1 (inhibitor) treated hepatic stellate cells to model pro-fibrotic activation and anti-fibrotic attenuation by small molecule inhibitor
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2019-12-21
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