New experimental results on bacterial growth inspire a novel top-down approach to study cell metabolism, combining mass balance and proteomic constraints to extend and complement Flux Balance Analysis
Stoichiometric models of metabolism, such as flux balance analysis (FBA), are classically applied to predicting steady state rates - or fluxes - of metabolic reactions in genome-scale metabolic networ
Fraction of positive average differences among flux-ordered pairs across the five data types employed, i.e. flux, transcript and protein levels and enzyme kcat values, for the three carbon sources and
Quek2014 - Metabolic flux analysis of HEK cell culture using Recon 2 (reduced version of Recon 2) This model is described in the article: Reducing Recon 2 for steady-state flux analysis