EGFR kinase domain mutant (T790M/L858R) with covalent ligand NS-062
收藏Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
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https://pdbj.org/mine/summary/5y25
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资源简介：
EGFR kinase domain mutant (T790M/L858R) with covalent ligand NS-062 Descriptor: (2R)-N-[4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]-1-(2-fluoranylethanoyl)pyrrolidine-2-carboxamide, Epidermal growth factor receptor Authors: Shiroishi, M, Abe, Y, Caaveiro, J.M.M, Sakamoto, S, Morimoto, S, Fuchida, H, Shindo, N, Ojida, A. Deposit date: 2017-07-24 Release date: 2018-07-25 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (3.102 Å) Cite: Selective and reversible modification of kinase cysteines with chlorofluoroacetamides. Nat.Chem.Biol., 15, 2019
创建时间：
2017-07-24
