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Mutant allelic series for human p53 ORF
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2014-11-24
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Lentiviral constructs expressing candidate tumoure suppressor genes were transduced into 697 cells. Of the candidates FOXO3, two isoforms of PRDM1 (⍺ and β) suppressed growth in-vitro and in-vivo. To
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Additional file 5: Table S5. of Concordance of copy number loss and down-regulation of tumor suppressor genes: a pan-cancer study
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Patterns of somatic uniparental disomy identify novel tumor suppressor genes in colorectal cancer
The aim of this study is to establish an integrative profiling of recurrent UPDs/UPPs, CNAs and genome-wide methylation status in sporadic CRC. Our results indicate that regions showing high frequenci
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WTX overexpression effect on gastric cell line
We used microarrays to detail the global gene expression in AGS gastric cancer cells overexpressing WTX, a tumor suppressor frequently inactivated in Wilms tumor. Results provide insight into roles fo
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