Drosophila Larval Brain Neoplasms Present Tumour-Type Dependent Genome Instability

we have investigated the mutational landscape of a cohort of tumors caused by mutations in l(3)malignant brain tumor (l(3)mbt), brain tumor (brat), aurora-A (aurA), and l(2)-giant larvae (lgl), which are some of the most aggressive and best characterized larval brain tumors that can be induced in Drosophila