aSamples were all assayed with a 30 min preincubation with inhibitor, and then MUNANA was added and reactions were stopped after 60 min and read. Samples were tested in duplicate and means and SDs for

Figshare2015-12-02 更新60

Hepatitis B virus mutation pattern rtL180M+A181C+M204V may contribute to entecavir resistance in clinical practice

病毒耐药性突变

抗病毒药物敏感性

Background and Aims: Entecavir (ETV) resistance of hepatitis B virus (HBV) conventionally requires rt184, 202, or 250 mutations plus lamivudine-resistance mutation (rtM204V/I ± L180M). This study aime

NIAID Data Ecosystem50

Antiviral susceptibility of clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) viruses from humans in the United States, October 2024 to February 2025

禽流感

抗病毒药物敏感性

Since October 2024, 55 human cases of influenza A(H5N1), clade 2.3.4.4b, were reported in the US. Sequencing of 46 viruses identified genotypes B3.13, D1.1, and D1.3. Virus genomes were analyzed for m

DataCite Commons2025-12-23 更新70

Drug susceptibility of rtM204Q and rtM204I mutants and wild-type strain.

抗病毒药物敏感性

病毒耐药性突变

EC50, 50% effective concentration of drug (µ mol/L).

Figshare2015-12-02 更新60