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Widespread inhibition of post-transcriptional splicing shapes the cellular transcriptome following heat shock. Mus musculus strain:3T3

NIAID Data Ecosystem2026-03-08 收录

热激应激转录组

RNA剪接调控

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA234529 数据链接链接失效反馈

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资源简介：

Heat shock timecourse RNAseq, 3T3 cells

应用场景：

创建时间：

2014-01-14

RNA剪接调控

METTL3

To identify changes in splicing patterns following METTL3 knockdown, RNA-sequencing was performed on nuclear RNA extracted from cells transfected with METTL3-targeting siRNA or a non-targeting siRNA (

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The transcriptional repressor, BCL11A, promotes breast cancer metastasis

癌症转移机制

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Identification of the BCL11A-regulated transcriptome and spliceosome and determination of MBNL1-dependent splicing changes by RNA-Seq Two/Three replicates were analyzed for each experimental condition

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The impact of Prp18p on splicing fidelity and efficiency in budding yeast

剪接保真度

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Fidelity of 3´-splice site (3´SS) selection by the spliceosome is critical for proper gene expression but is a daunting task considering the low complexity of the 3´SS consensus YAG. Here we show that

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Dynamics of RNA localization to nuclear speckles are connected to splicing efficiency [RNA-Seq]

RNA剪接调控

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Nuclear speckles, a type of membraneless nuclear organelle in higher eukaryotic cells, play a vital role in gene expression regulation. Using the reverse transcription-based RBP binding sites sequenci

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Widespread inhibition of post-transcriptional splicing shapes the cellular transcriptome following heat shock. Mus musculus strain:3T3

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