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Crystal Structure of the mutant Human ROR gamma Ligand Binding Domain With rockogenin.

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Protein Data Bank Japan2023-11-22 更新2026-03-21 收录
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Crystal Structure of the mutant Human ROR gamma Ligand Binding Domain With rockogenin. Descriptor: (1R,2S,4S,5'R,6R,7S,8R,9S,10R,12S,13S,16S,18S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-oxane]-10,16-diol, Nuclear receptor ROR-gamma, Nuclear receptor corepressor 2 Authors: Noguchi, M, Nomura, A, Murase, K, Doi, S, Yamaguchi, K, Adachi, T. Deposit date: 2017-03-03 Release date: 2017-06-07 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Ternary complex of human ROR gamma ligand-binding domain, inverse agonist and SMRT peptide shows a unique mechanism of corepressor recruitment Genes Cells, 22, 2017

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2017-03-03
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