Access to Different Isomeric Dibenzoxazepinones through Copper-Catalyzed C–H Etherification and C–N Bond Construction with Controllable Smiles Rearrangement
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https://figshare.com/articles/dataset/Access_to_Different_Isomeric_Dibenzoxazepinones_through_Copper_Catalyzed_C_H_Etherification_and_C_N_Bond_Construction_with_Controllable_Smiles_Rearrangement/2071369
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资源简介：
An efficient new way to access two
regio-isomeric dibenzoxazepinones is reported from 8-aminoquinoline
benzamides and 2-bromophenols. Through choice of conditions, the reaction
proceeds either through a sequential C–H etherification and
subsequent Goldberg reaction, both controlled by the aminoquinoline
group and Cu(I), or via a C–H etherification and subsequent
Smiles rearrangement promoted by Cu(II) and t-BuOK.
The 8-aminoquinoline moiety, e.g., 8-amino-5-methoxyquinoline, is
readily removable from the structures of dibenzoxazepinones under
moderate conditions.
创建时间：
2016-02-04
