Structure of Nek2 bound to CCT243779
收藏Protein Data Bank Japan2023-12-20 更新2026-03-21 收录
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Structure of Nek2 bound to CCT243779 Descriptor: 1,2-ETHANEDIOL, 5-{6-[(1-methylpiperidin-4-yl)oxy]-1H-benzimidazol-1-yl}-3-{[2-(trifluoromethyl)benzyl]oxy}thiophene-2-carboxamide, CHLORIDE ION, ... Authors: Mas-Droux, C, Bayliss, R. Deposit date: 2010-08-05 Release date: 2011-03-30 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Benzimidazole Inhibitors Induce a Dfg-Out Conformation of Never in Mitosis Gene A-Related Kinase 2 (Nek2) without Binding to the Back Pocket and Reveal a Nonlinear Structure-Activity Relationship. J.Med.Chem., 54, 2011
创建时间：
2010-08-05
