Prevalence for promoter CpG island hypermethylation of TOX subfamily of genes.

AMethylation of TOX was significantly more prevalent in breast than lung tumor (pTOX3 methylation was more common in lung than breast tumor (pBAmong NSCLC patients, the prevalence for TOX2 methylation in current smokers was significantly higher than never smokers (pCTOX3 methylation in primary lung tumors was marginally more prevalent in never smokers compared to current or former smokers (p = 0.05).DTOX3 methylation in primary lung tumors was more prevalent in squamous cell carcinoma compared to adenocarcinoma (p = 0.05).