IgG-specific vaccine-induced antibody responses per CHARGE patient.¹

1 All patients were vaccinated according to the Dutch or Belgian National Immunization Programmes [24,25], with the exception of patient CHD02 who had not been vaccinated. All vaccine titers were obtained without booster or recheck. 2 Patients who were not vaccinated for pneumococcal polysaccharides are shown in italic. 3 Concentration of antibodies to diphtheria or tetanus in IU/ml. A concentration ≥0.10 IU/ml is considered protective. Insufficient responses (<0.10 IU/ml) are shown in bold. 4 Concentration of antibodies to Haemophilus influenzae type b in mg/l. A concentration >1.0 mg/l is considered protective. Insufficient responses (<1.0 mg/l) are shown in bold. 5 Concentration of antibodies to pneumococcal polysaccharides in μg/ml. An adequate response to pneumococcal polysaccharides was defined as an absolute level >0.35 μg/ml in >50% of serotypes. Insufficient responses (<0.35 μg/ml) are shown in bold. Hib, Haemophilus influenzae type b; PPS, pneumococcal polysaccharides serotype; U, unknown IgG-specific vaccine-induced antibody responses per CHARGE patient.1