Transcriptome profiling of m6A mRNA modification in inflammation of bovine mammary epithelial cells infected by Staphylococcus aureus and Escherichia coli. Transcriptome profiling of m6A mRNA modification in inflammation of bovine mammary epithelial cells infected by Staphylococcus aureus and Escherichia coli

Mastitis is a common disease in dairy cows and brings massive losses to the dairy industry. m6A is a type of modification strongly associated with many diseases. However, the role of m6A in mastitis caused by Staphylococcus aureus and Escherichia coli has not been investigated.We used MeRIP-seq technology to sequence the bovine mammary epithelial cells (MAC-T) infected with inactivated S. aureus/E. coli for 24 h. Overall design: meRIP-seq, RNA-seq for bovine mammary epithelial cells (MAC-T) infected by inactivated S. aureus and E. coli for 24h