Recruited blood monocytes contribute to the establishment, perpetuation and resolution of tissue inflammation. Specifically, in the inflamed intestine, monocyte ablation was shown to ameliorate coliti
Subconfluent NCI-H292 cells and PBECs were stimulated with different TLR agonists at indicated concentrations (��g/ml) or SFM for 24 h; thereafter cell proliferation was analyzed by a BrdU ELISA-based
Background: The Toll-like receptor (TLR) family is involved in the recognition of and response to microbial infections. These receptors are expressed in leukocytes. TLR stimulation induces the product
The breakdown of toll-like receptor (TLR) tolerance results in tissue damage. Here we provide evidence that membrane bound O-acyltransferase domain containing 7 (MBOAT7) is a crucial negative regulato
