Results for the three independent runs of automated linear modeling with evolutionary measures as dependent variable for the 275 base pathways.

The following variables have been considered by the model: 3 gene sequence properties, effective number of codons (ENC), gene length (Length) and CG content (CG); and 4 topological centralities: closeness, betweenness and in-degree and out-degree centralities. Beta coefficients and P-values (between brackets) are reported; significant values according to a threshold of 0.05 are presented in bold.