Additional file 12: Table S9. of Machine learning classifier for identification of damaging missense mutations exclusive to human mitochondrial DNA-encoded polypeptides

Amino acid substitutions with no clear evidences of pathogenicity. Mutations are described by the polypeptide amino acid position (AA Position), wild type amino acid (WT AA), mutant amino acid (MUT AA) and affected gene (Gene). Predicted phenotype of Mitoclass.1 is included. The next four columns summarize the prediction result (P, positive/damaging; N, negative/neutral) for the four tested predictors. The last column (Count) indicates the number of predictors with the same damaging phenotype output. (XLS 31 kb)