Nfib promotes Metastasis through a Widespread Increase in Chromatin Accessibility [ATAC-seq]
收藏NIAID Data Ecosystem2026-03-11 收录
下载链接：
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE81255
下载链接
链接失效反馈官方服务：
资源简介：
We describe Nfib as an important regulator of chromatin accessibility in Small cell lung cancer (SCLC). ATAC seq was performed on [1] ex vivo samples from primary tumors and metastases of a mouse model for SCLC (4 samples of each plus technical replicates of 7 samples for a total of 15 samples) [2] cell lines derived from mouse models for SCLC. [3] Nfib loss of function in murine SCLC cell lines (shLuc are controls, sh2 is shRNA that knocks down Nfib) [4] Nfib gain of function in murine SCLC cell lines and human SCLC lines (empty indicates control cells, Nfib indicates cells overexpressing Nfib)
创建时间：
2019-05-15
