MYT1L loss leads to chromatin structures and transcriptome alterations in mouse hypothalamus [RNA-Seq]
收藏Alliance of Genome Resources2026-08-01 收录
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MYT1L Syndrome mouse model displays obesity as observed in MYT1L patients. Utilizing this mouse model, ATAC-seq and RNA-seq on adult mouse hypothalamus reveals molecular alternations related to feeding behaviors, which might contribute to obesity phenotype. We have 3 biological replicates per genotype for ATAC-seq and 6(Het)/5(WT) replicates for RNA-seq on adult mouse hypothalamus
