Gene regulation in a novel therapeutic approach that involves ceramide-induced apoptosis pathways

ChEBI2009-08-27 更新2026-07-21 收录

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-17525 数据链接链接失效反馈

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Gene regulation in a novel therapeutic approach that involves ceramide-induced apoptosis pathways

创建时间：

2009-08-27

Induction of Bcl-x(L) Expression by Human T-Cell Leukemia Virus Type 1 Tax through NF-κB in Apoptosis-Resistant T-Cell Transfectants with Tax

HTLV-1病毒致癌机制

细胞凋亡调控通路

Human T-cell leukemia virus type 1 (HTLV-1) Tax is thought to play a pivotal role in immortalization of T cells. We have recently shown that the expression of Tax protected the mouse T-cell line CTLL-

PubMed Central50

A Cardinal Role for Cathepsin D in Co-Ordinating the Host-Mediated Apoptosis of Macrophages and Killing of Pneumococci

宿主-病原体相互作用

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The bactericidal function of macrophages against pneumococci is enhanced by their apoptotic demise, which is controlled by the anti-apoptotic protein Mcl-1. Here, we show that lysosomal membrane perme

NIAID Data Ecosystem40

Herpes Simplex Virus Type 1 Blocks the Apoptotic Host Cell Defense Mechanisms That Target Bcl-2 and Manipulates Activation of p38 Mitogen-Activated Protein Kinase To Improve Viral Replication

病毒免疫逃逸机制

细胞凋亡调控通路

Wild-type (wt) herpes simplex virus type 1 (HSV-1) suppresses cell death. We investigated the apoptotic pathways triggered during infection with mutant viruses tsk and 27lacZ (which lack functional IC

PubMed Central20

Systems Biology of Tissue-Specific Response to Anaplasma phagocytophilum Reveals Differentiated Apoptosis in the Tick Vector Ixodes scapularis

蜱传病原体宿主互作

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Anaplasma phagocytophilum is an emerging pathogen that causes human granulocytic anaplasmosis. Infection with this zoonotic pathogen affects cell function in both vertebrate host and the tick vector,

NIAID Data Ecosystem50

Crystal Structure of MC159 Reveals Molecular Mechanism of DISC Assembly and vFLIP Inhibition

蛋白质晶体结构解析

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Crystal Structure of MC159 Reveals Molecular Mechanism of DISC Assembly and vFLIP Inhibition

NIAID Data Ecosystem30