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Mechanisms of suberoylanilide hydroxamic acid inhibition of mammary cell growth

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PubMed Central2000-12-22 更新2026-04-25 收录
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https://pmc.ncbi.nlm.nih.gov/articles/PMC13923/
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资源简介:
The mechanism of suberoylanilide hydroxamic acid in cell growth inhibition involved induction of pRb-2/p130 interaction and nuclear translocation with E2F-4, followed by significant repression in E2F-1 and PCNA nuclear levels, which led to inhibition in DNA synthesis in mammary epithelial cell lines.
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BMC
创建时间:
2000-12-22
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