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Table S1 from The SETDB1–TRIM28 Complex Suppresses Antitumor Immunity

Figshare2021-12-01 更新2026-04-28 收录

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https://figshare.com/articles/dataset/Table_S1_from_The_SETDB1_TRIM28_Complex_Suppresses_Antitumor_Immunity/22544600 数据链接链接失效反馈

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Table S1 shows the results of A CRISPR/Cas9 screen for chromatin regulators of PD-L1 expression

应用场景：

创建时间：

2021-12-01

白血病发病机制

CRISPRi筛选

Investigating Bcor target genes in BcorΔE9-10KrasG12D leukaemia with a custom CRISPR dropout screen BcorΔE9-10KrasG12D cell line was transduced with a custom CRISPR library and a dropout screen was pe

NIAID Data Ecosystem30

Genes of CRISPR-Cas9 negative screening.

CRISPRi筛选

肿瘤免疫逃逸

We compared changes in sgRNA abundance between T24 cells challenged and unchallenged by CD8+ T cells, and then performed negative screening (p < 0.01, log2Fold change < −1.0, and good sgRNAs ≥ 5). (X

NIAID Data Ecosystem10

Genome-wide CRISPR screen of post-transcriptional regulators of IL6 3'UTR

CRISPRi筛选

IL6转录后调控

The aim of this research is to uncover novel post-transcriptional mechanisms regulating IL6 3'UTR. IL6 is one of the most essential cytokines and its expression is tightly controlled during acute and

NIAID Data Ecosystem10

Essential gene profiles for human pluripotent stem cells identify uncharacterized genes and substrate dependencies. Mair et al.

干细胞鉴定

CRISPRi筛选

Human pluripotent stem cells (hPSCs) provide an invaluable tool for modeling diseases and hold promise for regenerative medicine. For understanding pluripotency and lineage differentiation mechanisms,

NIAID Data Ecosystem20

TNF-NFkB-p53 axis restricts in vivo survival of hPSC-derived dopamine neuron (CRISPR screen). TNF-NFkB-p53 axis restricts in vivo survival of hPSC-derived dopamine neuron (CRISPR screen)

帕金森病细胞移植

CRISPRi筛选

First-in-human clinical trials illustrate the feasibility and translational potential of human pluripotent stem cell (hPSC)-based cell therapy in Parkinson’s disease (PD). However, a major unresolved

NIAID Data Ecosystem10

Table S1 from The SETDB1–TRIM28 Complex Suppresses Antitumor Immunity

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