High-resolution H&E images from the HistoSweep study across multiple tissues and diseases

his dataset contains eight high-resolution hematoxylin and eosin (H&E) stained tissue images used in the study HistoSweep enables cellular-resolution tissue quality control for gigapixel images in digital pathology and spatial omics. The images have been pre-processed by scaling and padding to ensure consistency across samples and compatibility with digital pathology workflows. Contents Lung atypical adenomatous hyperplasia (AAH) (contributed by K. Human laboratory) Lung_AAH.zip Atherosclerosis (three samples, contributed by L. Maegdefessel laboratory): Three samples: post Xenium profiling, post CODEX profiling, multi-sample tissue post CODEX profiling Artery_Atherosclerosis.zip Lymph node from melanoma patient (contributed by A. Huang laboratory) LymphNode_Melanoma.zip Kidney with renal cell carcinoma (RCC) (contributed by A. Huang laboratory) Kidney_RCC.zip Kidney tissues processed with CosMx (contributed by K. Susztak laboratory): One image containing two normal samples One image containing a normal and a type 2 diabetes (T2D) sample Kidney_MultiSample_T2D.zip PurposeThese images provide a diverse set of gigapixel H&E slides spanning multiple tissue types and disease contexts. They serve as a resource for reproducing, validating, and extending the analyses performed with HistoSweep, as well as for general use in histopathology and spatial omics research.