BMI1 drives metastasis of prostate cancer in Caucasian and African-American men and is a potential therapeutic target: hypothesis tested in race-specific models

MDA-PCa2b cells were treated with PCT-209 or control (DMSO) for 24h and subjected to the qRT-PCR based microarray analysis (Qiagen, Germantown, MD). qPCR gene expression profiling. Metaststic African american prostate cancer cell line MDA-Pca2b cells were treated with BMI-1 inhibitor PTC-209 or control as indicated in the summary. Equal amount total RNA from Treated and control was used for gene expression analysis.