Ras guanine nucleotide exchange factor SOS1 (Rem-cdc25) in new crystal form
收藏Protein Data Bank Japan2024-01-17 更新2026-03-21 收录
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https://pdbj.org/mine/summary/5ovd
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Ras guanine nucleotide exchange factor SOS1 (Rem-cdc25) in new crystal form Descriptor: 1,2-ETHANEDIOL, Son of sevenless homolog 1 Authors: Hillig, R.C, Moosmayer, D, Hilpmann, A, Bader, B, Schroeder, J, Wortmann, L, Sautier, B, Kahmann, J, Wegener, D, Briem, H, Petersen, K, Badock, V. Deposit date: 2017-08-28 Release date: 2019-02-06 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
创建时间：
2017-08-28
