Data Supporting PhD Dissertation: Translational Medical Device Development in Vascular Access for Haemodialysis

This dataset contains the raw data used in the chapters of the TU Delft/LUMC Dissertation of Nick White entitled Translational Medical Device Development in Vascular Access for Haemodialysis. Data is sorted into folders for the relevant chapters. Each chapter folder contains a README describing the data.<br>The research aim is to develop and evaluate a novel medical device for improved vascular access for haemodialysis. 6 Chapters are included:A medical device development framework is developed that includes an example device. Photos are included that demonstrate developmental steps undertaken with the example deviceAn in vitro study on safety of administration of contrast media through central venous catheters. The data includes pressure measurements of the catheters and electron microscopy images of the luminal catheter surfacesA literature review on haemodynamics vascular access for haemodialysisA clinical study on intraoperative optimization of arteriovenous fistula surgery. Patient data is used for this Chapter, which is not included in the dataset for privacy reasons. A README is included with contact information to access data upon request. A design study that develops and tests a new type of implantable medical device for vascular access for haemodialysis. The data includes measured torque and force data measured on the device to assess benchtop functionality.A small-scale pilot in vivo study with the implantable medical device developed that focuses on design improvements, feasibility and functionality. The data includes photos taken of the implantation and explantation of the device, and ultrasound images taken throughout the study period of 13 weeks.<br><br>

本数据集包含尼克·怀特（Nick White）于代尔夫特理工大学/莱顿大学医学中心（TU Delft/LUMC）所撰博士学位论文《血液透析（haemodialysis）血管通路（vascular access）转化医疗设备开发》各章节所使用的原始数据。数据按对应章节分类存储于不同文件夹中，每个章节文件夹内均附带一份README说明文档，用于介绍该章节对应的数据内容。
本研究的目标为开发并评估一款用于优化血液透析血管通路的新型医疗设备。本数据集共涵盖6个章节的相关内容：
1. 构建了一套包含示例设备的医疗设备开发框架，并配有展示该示例设备研发全流程的实拍照片。
2. 一项关于经中心静脉导管（central venous catheters）注射造影剂安全性的体外研究（in vitro study），数据集包含导管压力测量数据以及导管内腔表面的电子显微镜（electron microscopy）图像。
3. 一篇关于血液透析血管通路血流动力学的综述文献。
4. 一项关于动静脉瘘（arteriovenous fistula）手术术中优化的临床研究。本章节使用了患者数据，但出于隐私保护考量，相关患者数据未纳入本数据集。该章节附带一份README说明文档，其中包含可申请获取数据的联系方式。
5. 一项设计研究，旨在开发并测试一款用于血液透析血管通路的新型植入式医疗设备（implantable medical device），数据集包含用于评估台架测试功能的设备扭矩与力测量数据。
6. 一项针对该植入式医疗设备的小型体内预试验研究（in vivo study），重点关注设计改进、可行性与功能表现。数据集包含设备植入与取出过程的实拍照片，以及为期13周的研究周期内采集的超声图像。