CD45- sorted tumor cells from RANK+/+ and RANK-/- MMTV_PYMT late carcinomas

Transcriptional profile of either RANK+/+ or RANK-/- MMTV-PyMT late carcinomas, orthotopically injected in syngeneic RANK+/+ mice. Once host mice developed tumors, CD45- tumor cells were sorted by flow cytometry in order to compare changes on tumor gene expression caused by the absence of RANK protein. Two-condition experiment: RANK+/+ (WT) vs. RANK-/- (KO) MMTV_PYMT CD45- sorted tumor cells. Biological replicates: 3 RANK-/- replicates, 3 RANK-/- replicates. Two technical replicates from each sample (A and B).