Huntingtin associated protein (HAP1) is a cGMP-dependent kinase anchoring protein (GKAP), specific for the cGMP-dependent protein kinase Iβ isoform.
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https://www.omicsdi.org/dataset/gpmdb/GPM32320007631
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资源简介：
Data from ProteomeXchange, PXD ID: PXD001434. Published as part of J Biol Chem. 2015 Feb 4. pii . From the Abstract: {{i}} ... Here, we extend on this cAMP-based chemical proteomics approach, employing competitive concentrations of free cyclic nucleotides to isolate each kinase and its secondary interactors. Using this approach we identified Huntingtin associated protein 1 (HAP1) as a putative novel GKAP. Through sequence alignment with known GKAPs and secondary structure prediction analysis we defined a small sequence domain mediating the interaction with PKG Iβ, but not PKG I alpha ... {{/i}}
创建时间：
2015-02-10
